Safety, Tolerability, and Pharmacokinetics of KP-1461 in Phase I Clinical Studies
Background: KP-1461 is a prodrug 1 Piece Leather Suits to KP-1212.KP-1212 is a viral mutagen designed to increase viral error rate.Methods: We describe 2 phase I studies: KP1461-101 (double-blind, placebo-controlled, single, escalating doses, 100 to 1600 mg study in 42 non-HIV-infected participants) and KP-1461-102 (double-blind placebo-controlled